Endocrine Disruptors in the NYT

Nicholas Kristof wrote about endocrine disruptors in his column this weekend. He cites some of the evidence for disturbances in sexual development -- "bizarre deformities in water animals" -- and accumulating evidence of the same disturbances occurring in humans.

Acronym Required first wrote about endocrine disruptors back in 2005, with Plastic Bottles- Protecting Your Baby, by the ACC". Hundreds of studies in the past 20 years have documented disturbing effects of endocrine disruptors, which are widely used in industry and agriculture to make the food you eat, the containers you eat out of, and the products that surround you as you sit and read this post. Endocrine disruptors act like hormones to effect physiological actions in species from fishes to humans. Here's some of the evidence Kristof cites from the research literature on different chemicals:

  • "Frogs, salamanders and other amphibians began to sprout extra legs."

  • "In heavily polluted Lake Apopka, one of the largest lakes in Florida, male alligators developed stunted genitals."

  • Researchers found in 2003 that "in the Potomac watershed near Washington, male smallmouth bass have rapidly transformed into "intersex fish" that display female characteristics." Today 80% of these male fish lay eggs.

  • Scientists are concerned with "large increases in numbers of genital deformities among newborn boys."

  • "7 percent of boys are now born with undescended testicles, although this often self-corrects over time."

  • "And up to 1 percent of boys in the United States are now born with hypospadias, in which the urethra exits the penis improperly, such as at the base rather than the tip."

  • "DES, a synthetic estrogen given to many pregnant women from the 1930s to the 1970s to prevent miscarriages, caused abnormalities in the children."

  • "evidence from both humans and monkeys [suggests] that endometriosis, a gynecological disorder, is linked to exposure to endocrine disruptors."

  • "Researchers also suspect that the disruptors can cause early puberty in girls."

  • "research has also tied endocrine disruptors to obesity, insulin resistance and diabetes, in both animals and humans."

  • "mice exposed in utero even to low doses of endocrine disruptors appear normal at first but develop excess abdominal body fat as adults."

  • Kristof notes a recent statement from the Endocrine Society. The group of scientists says: "In this first Scientific Statement of The Endocrine Society, we present the evidence that endocrine disruptors have effects on male and female reproduction, breast development and cancer, prostate cancer, neuroendocrinology, thyroid, metabolism and obesity, and cardiovascular endocrinology."

  • Kristof quoted Dr. Ted Schettler of the Science and Environmental Health Network, who said, "'this can influence brain development, sperm counts or susceptibility to cancer, even where the animal at birth seems perfectly normal."'

There's a lot more evidence showing that chemical disruptors produce widespread harm over the environment to produce abnormal reactions. As one John Hopkins scientist told Kristoff: "It's scary, very scary."

But in a completely curious turn, halfway through the article, Kristof capitulates to the winds of "50-50 science journalism". Here's how "50-50 science journalism" works.

  1. Accumulate your evidence.
  2. Make a strong case for your point, citing the evidence.
  3. Then abruptly cripple your whole point, smash it across the knees, by writing a one or two statements for the "other side", thus appeasing some readers and advertisers.

Kristof writes: "The scientific case is still far from proven, as chemical companies emphasize, and the uncertainties for humans are vast." To be fair, Kristof's reference to the "other side" could be considered merely a polite and politic mention. "Vast uncertainty" for humans could mean anything. But even at best this doesn't line up with the rest of his article and all the evidence he cites. What about his lists of studies?

Scientists are "connecting the dots" he writes. I know this may sound trifling but scientists are well into the data. It's only recently that the public is realizing that this problem is real -- a realization that's more substantial, quite un-dot-like. Some journalists are farther behind, but again, the evidence is accumulating at a brisk pace.

My small reservations with his article aside, Kristof often takes on controversial issues, especially in international development, that are easy for the mainstream press to ignore. While coverage of bisphenol A is surprisingly robust, now that states and cities have initiated legislation restricting its use, the larger questions of pervasive chemical use without regulation remain largely ignored. Importantly, this topic has been very easy for federal agencies to ignore. Therefore, it's great to see coverage of endocrine receptors by an influential New York Times journalist who will help inform the public, who will in turn demand that government act more aggressively on chemical oversight.

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Acronym Required writes frequently on journalism that remains faithful to all sides of science policy issues despite the evidence, for instance Climate Change: Fueling the "Debate", "Science Editors Sell You Short", and Phthalates and Bisphenol A: Media and Politics

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