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Why Can't We Be Friends? The Pepsi Wars.

The skirmish over at ScienceBlogs between PepsiCo and the science bloggers actually made me feel sorry for Pepsi.

Pass The Bong and the Aspartame

You have to admit, PepsiCo had a tough month...week. First, San Francisco Mayor Gavin Newsom banned Pepsi from vending machines, a move that elicited potshots from conservative DC paper The Washington Times, as in: "Pass The Pot Brownies, But Drop That Soda". Expounding on that clever cliche, they wrote: "In the City by the Bay, it may soon be easier to get a pot-laced brownie than a can of Pepsi".

Oh yeah, nailed it! Hippies in the "City By The Bay" ("Frisco" to some) -- don dirty tie-dyed t-shirts daily, in order to stand on corners and flash "peace" fingers to badly parented long-haired youth driving orange Volkswagon buses, wearing flowers in their hair, swaying to the music, THC soothing their psychedelics' addled nerves. Wow, The Washington Times sure knows "The City By The Bay".1

It used to be that Coke would lose its big university or city contract to Pepsi, then Pepsi to Coke, back and forth. But not this time, soda was ousted. No sooner than being ejected from San Francisco city vending machines, PepsiCo was yelled off ScienceBlogs. Curiously, ScienceBlogs also hails from the Bay Area.

SciBling Hospitality?

It must have been a confusing time for PepsiCo. First, warmly courted by ScienceBlog editors, PepsiCo invitingly titled their blog "Food Frontiers". But they couldn't even pen a "Hello, World! Corn syrup is so good for you", before "SciBlings" (ScienceBlog bloggers) rose up en masse from their virginal science blog space and confronted the evil sugar-water mixer about stealth advertising. (If you can do stealth with prominent branding, that is.)

I wasn't there. But it's mid-July, pretty slow in science news, so I thought I'd Twitter all the anger, consternation, then mass exodus of 20 SciBlingers, thus entertaining all the fluffy dogs, porn stars (and some cool peeps) who follow AcronymRequired. Unfortunately, before anyone could figure out whether to call it PepsiCoGate, Pepsigate, or Pepsicopalyse, Pepsi Food Frontiers skedaddled as if confronted by a battalion of helmeted storm troopers spraying plastic bullets and tear gas at their sit-in.

Safely back at PepsiCo.com, Food Frontiers publicly reminisced about the "very candid feedback" and their "intent to embrace that conversation". The regrouping Pepsi bloggers talked microbial stability, acidity, phosphorous content, obesity, and salt, vis-a-vis PepsiCo. And as promised, they engaged "that conversation", by answering the demands of SciBlingers who chased them back.

PepsiCo "embraced" the bracing blog comments from SciBlingons ("Does the material leave your own computer when you write a post, ever? I.e, pass in front of other people's eyes? Is there a standard workflow for producing a blog post that involves any kind of oversight or inspection?...The truth is that if you'all blogging researchers can only write approved copy, then the whole blog thing really is probably a bad idea"), and responded promptly and sweetly: "Thanks Greg Laden" in "The Posting Process on Food Frontiers".

But will such sugary pabulum engage ScienceBloggers? No. Only two comments to that PepsiCo post, neither of them reciprocally "embracing". It would have been more SciBlingy for Food Frontiers to be a little in their face: "WTF is YOUR process -- why do so many ideas conflicting with your world view meet with such profane outbursts and bunkerbuster-style attacks? What are you, the Department of OK Blogs?" -- Now that, would be "engaging the conversation", sciblingy-like. Instead, light, huggy, bubbly, marketing stuff.

Maybe Food Frontiers bloggers were jittery, wan and weak from a diet of caffeine, phosphorous, sugar, water, and natural flavors. Or, possibly they were devouring cans of spinach voraciously and weight-training vigorously, but saving their vim and vigor for this week's attack on a more familiar foe -- CocaCola.

In a newish YouTube spot, the two opposing soft drink truck drivers meet in a diner and swap colas, "Why Can't We Be Friends?" by the band War, a 1970's song. As one driver drinks a soda, the other betrays him (can't tell you why). Then they get mad and crash through a window together. The Associated Press wrote:

"Analysts say people love the funny, spirited rivalry of the decades-old cola wars and the move will benefit both soda makers. That's good news for the $100 billion industry, which is seeing weak soft drink sales as shoppers switch to healthier juices and teas."

Business as usual, just pining for the 1970s? See how it works Sciblingers? Friendly public rivalry.

Butlered off the Isle?

Of course, I don't really feel sorry for Pepsi. They have a nice new sepia toned 1970's ad and a brilliant business, patenting and selling corrosive sugar and water drinks. But as we've written before, soda's not so healthy for humans or the environment ("Childhood Obesity, The American Way", or "Pop's Out Drug's are In", or "Coke: Teaching the World to Sing", or "Why So Fat? It's System Wide", or "Common Sense Foods in Schools""). And PepsiCo doesn't need us, they can always fall into the arms of Coke, or the loving the Cato Institute. or FOX, and many others.

Apparently there was more going on at ScienceBlogs than PepsiCo, there always is. I've read and mostly enjoyed ScienceBlogs since the inception. There weren't too many bloggers way back then and I've watched SB evolve with particular interest. So I get it. But Sciblingons! Sheesh! "Spirited rivalry" and gentle brawls people! Do you really need to beat them up, throw them off the island, bash their heads in, then drown them? What good are they too you then?

Just my opinion. I believe that ScienceBlogs has done wonders for getting others online writing about science. A ton of SB bloggers blog seriously about science, every day, good stuff. But some bloggers get increasingly spiteful as they vie for the attention that blogging compels, then use that attention to generate a certain brand of PR for SB. The level of conversation often spirals downward (there must be some entropy model that describes it). And that downward spiral seems infectious -- I've noticed Nature has been forging new ground lately in diluting their brand with some profane blogs also.

Pepsi's not the first one to feel SciBlingon wrath, though sleepy-hot July always gives these incidents an extra charge. Remember the Nature/Butler/PLoS fracas of July, 2008? It was similarly acrimonious with a familiar corporate/underdog theme.

These bloggers know their power, they say. But this is how SB looks from the outside, to me, an independent sometimes-blogger. Everyday science bloggy, bloggy, bloggedy, great - oh, too boring? Yawn? Then Boom, Smash, Bang, big tizzy over at ScienceBlogs over something, lots of media coverage. Repeat. For someone not in the thick of it, the episodic commotions tempt a plea for perspective.

I hope ScienceBlogs settles -- certainly finding eager writers shouldn't be a hurdle, and there are 60 left. I look forward to future writing from the diaspora. But I would also venture that it's complicated, messy business, this advertising stuff, this ethical boundaries stuff. It's pretty easy to inadvertently be seen as hypocritical trying to carve arbitrary ethical boundaries that suit your own very personal interests. As a minor, minor example, isn't most blogging just personal branding/advertising? But your brand is pure as the driven snow, whereas Pepsi's is marred by soda pop? Anyway, I'm not sure getting Pepsi off of ScienceBlogs, although certainly a "cause", was one worthy of the show or the arena.

(To Be Continued)

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1 Actually, in another "City By The Bay", they plan to grow pot by the acre, an unfortunately timed news story which you'd think would crush my defense. But then the city will tax it, hopefully so they can pay for a much needed police force. Complicated. Another story.

Old vs New Newsrooms, Sides of Maggots, and Lady Gaga

Gene Weingarten on the old "typical American newsroom" versus the "New Newsroom", in "Gene Weinharten Column mentions Lady Gaga" (via BoingBoing, via Joel Johnson).

Weingarten misses deadlines and creative headlines, but appreciates "the services of tens of thousands of fact-checking 'citizen journalists'", and "comments" -

"though they can seem a little jarring: spit-flecked rants that are appended to a product that at least tries for a measure of objectivity and dignity. It's as though when you order a sirloin steak, it comes with a side of maggots".

"New Journalism" is "confusing", with leagues of "multiplatform idea triage specialists", compared to the old days, when:

"On deadline, drunks with cigars wrote stories that were edited by constipated but knowledgeable people, then printed on paper by enormous machines operated by people with stupid hats and dirty faces."

There's more.

Gateway Drug News

In our break from blogging we learned about an unexplored benefit of writing about news, as we do at Acronym Required (from time to time). When we spend "free" time writing or interpreting news we care about we interrupt any potential habit of seeking substantive news amongst the addictive trifle of mainstream media. Not to disparage all MSM, of course, some MSM is great. ProPublica publishes great pieces (though not quite mainstream). There's Huffington Post's Investigative Fund. But trash news is the bread and butter of MSM (and Huffpo proper), because readers are addicted to piffle.

Haggis

Case in point: At Reuters, often a fine reporting vehicle, readers devoured the piece "The Hills Are Alive With Haggis". Haggis, you ask? Indeed. Scots consume Haggis a dish made from the lung, liver and heart of a sheep, on Burns night - of course, with lots of whiskey.

An aside: The US banned haggis in 1989 because of the threat of bovine spongiform encephalopathy (BSE), but for some reason unexplored by Reuters, the US recently relaxed the ban. Richard Lochhead, the Scottish environmental secretary waxed ecstatic that Americans can now "sample our world-renowned national dish."

But Reuters did not cover the American ban of sheep innards because of BSE. Readers can only learn that "renowned" as it may be, many Scots don't know what haggis is and Brits are even more uninformed. As the report goes, one in five Brits thinks haggis is "an animal that roams the Highlands", another 18% think it's a Scottish instrument, and 4% think its a character from Harry Potter.

Circuses and More

Like the empty calories of cotton candy, apparently, the haggis story leaves readers hungry for more drivel. Because from "The Hills Are Alive With Haggis", they're unlikely to click on a story about the environmental crisis off the Louisiana coast or the implications of Greek financial crisis. No, says Reuters "after reading this article people will most likely read": "Police barred from penis enlargement", about Indonesian police candidate screening, that even I refuse to link to. Rather that exploring the BSE ban, they'll more likely read: "Circus comes to Turkmenistan again after long ban."

Just like any perilous addiction, it seems that reading banal news leads to reading even more rotten gibberish. Of course, as we've just inadvertently demonstrated, bloggers, once heralded as the saviors of news, are JUST AS PRONE to courting readers with the most scurrilous news they can drum up. But we do try to do better. (This post not included). We try to write about science.

News: Fit To Print or Print to Fit?

Twitter Changes Our Brains:

In "Cut This Story", Michael Kinsley writes that "newspaper articles are too long", whereas internet news stories "get to the point". In 1,809 words Kinsley calls out the vagaries and customs of print journalism, sniping at long articles filled with what he judges useless information. In one 1,456 word The New York Times story, the fluff surrounding the facts about the House Health Care Plan annoys him: "Fewer than half the words in this opening sentence are devoted to saying what happened", says Kinsley. He runs a tally of words he judges wasteful in various news articles: 1,2

"The quote is 11 words, while identifying Miller takes 10"..."Quote: 18 words; identification: 21 words"..."Quote: 16 words; identification, 19 words"..."The first 13 words of the piece with tired rhetoric"..."56 words spent allowing Jesse M. Brill to restate the author's point."

Is it a Twitter induced compulsion, first editing down to 140 characters, then getting stingy about words? As you can see, Kinsley's especially peeved about the use of quotes from experts, which he calls "unnecessary verbiage". He cites a NYT reporter who quotes compensation expert "Jesse M. Brill" -- a "total stranger". Reporters should just state their opinions, he says, instead of running them through proxy "experts", noting we only trust Brill because we trust the reporter, the editor, and the paper. In fact, we should cut out Brill, the "middleman", and other experts.

So then we'd be talk radio for readers?

Journalists tend to disagree with Kinsley. One Columbia Journalism Review writer argues that quotes from experts show a reporter has done their homework. Like Kinsley I have issues with experts, though I disagree with CJR's idealistic interpretation of their implementation. But "experts" serve many purposes, even if papers often deploy them egregiously.

As Kinsley points out, the use of experts often fails to ensure any reporting standard. But experts provide journalists with a dependable structure for stories, that they can file under deadline. Expert quotes in stories also give readers of varying opinions something to latch on to, which guarantees papers more subscriptions. One negative outcome of dependence on experts is that we're left subject to manipulation, experts can be used as tools by papers, lobbyists and politicians. But with careful attention to experts' backgrounds, smart readers can quickly understand the particular slant of the story. All to say that the use of experts doesn't waste newspaper space and it would be simplistic to conclude readers move online because articles are too long.

Balance of Evidence vs. Journalistic Balance

In our area of science and technology, journalists report the science in public policy stories like global warming and bisphenol A safety, with necessary journalistic traditions of "balance", "both sides", and statements from "experts". But most often they fail to relay important keystones to understanding science, like the more important "balance of evidence". For example, the balance of evidence supports global warming, although scientists disagree about some details and likely outcomes.

Furthermore, papers routinely identify policy advocates or lobbyists as "scientists" with dependable expertise because they hold a Ph.D., M.D., or other credential, but pay no heed to experts' affiliations or politics, which often provide the only meaningful information. Lobbyists in the global warming arena appear often in newspaper stories, although an opinion from Exxon-Mobil often doesn't offer credible science, rather an opinion as an "expert" on a certain policy preference.

In any area of science there is always valid disagreement, even when the preponderance of evidence tips to one high-level conclusion. But smaller disagreements don't necessarily make a "side" or provide "balance", except in the world of journalism. Journalistic balance seen through scientists' eyes often fails because it abandons accuracy and amplifies trivial opinions, seemingly on account of an editor who lacks the time or guts to report the balance of evidence.

The Cut-throat Non-buyer's Market

Kinsley writes that attributing journalists' opinions to "experts" is as useless as "legacy code" in software programs. However true that expert opinions sometimes fail to hit the mark, sometimes it's critical to leave legacy code in the program, and if we're using analogies, some introns, "non-coding" or "junk" regions of DNA sequence, turn out to be important. Similarly, in more ways than one, the use of experts quotes is also important.

Like many papers that serve(d) as community anchors, New York Times serves as more than a source of "news" or a collection of facts. Rather, readers see it as a faithful morning companion, a little arts and entertainment, some sports maybe, business. Faithfully, whenever some meme floats around, the Times picks it up and ferrets out an expert somewhere to tell you that yes, what you suspected/heard/rumored/hoped/feared is true. The paper grounds stories with quotes and uses experts of opposing views to give readers choices and validate those choices with authority.

Global warming may wipe out your vacation home, but the NYT won't feed you that news with your morning coffee without some "balance". Can't stand the idea of your seaside resort washing away? Don't worry, the NYT has an expert just for you. The right expert, no matter how unreliable, can soften what would otherwise be scary news. Faux conflict that drives scientists nuts about media coverage, reassures readers and reinforces the status quo.

Also to maintain expectations and satisfy readers, papers sometimes add flourish to stories that say nothing. Kinsley rakes through Times and Post articles about healthcare reform, mocking the "sweeping" this and "hard-fought" that. He chastises one author for including what he judges unnecessary quotes from Republicans who unsurprisingly oppose reform. Funny enough, but what else would the paper tell readers? "Congress struggled for months and ended up with a meaningless bill that won't go anywhere? Wake up and smell the coffee?"

And of course if you're 50% of the population who counts yourself as a Republican, you don't want Kinsley's stripped down version, the "duly reported fact that all but one [Republican] voted against [healthcare reform]". You want the paragraph Kinsley would delete, the one with a Republican citing their talking points on healthcare: "more taxes", "more spending". You're glad to read that a Republican "relentless criticized" the "Democrats' plan", because later in the day, you'll do the same, listeners willing. The NYT can't cut out these bits because it needs to assure whatever conservatives it can cling on to, that it's a good morning in America.

Andrew Cohen, of The Atlantic Monthly also takes exception to Kinsley's assessment of experts. Brill's expertise is valuable, he writes, as is his own (Cohen frequently serves as a legal expert), and "straight news articles should include analysis from experts like Brill" (and him). Speaking as a legal expert he enjoys both being quoted and knowing the politics of other quoted legal experts, his peers. His seems like a defense of the Times as the Facebook for middle-aged lawyers, which reinforces my point. The NYT is a comfortable gathering place where you can feel good about yourself. Republicans may call it a liberal rag, but they still get representation.

Happy readers, even ones with unjostled minds are valuable. There are other sources if readers want to bang their heads against walls with harsh, uninsulated facts, but the NYT needs subscribers.

Years of Magical Thinking

Keeping readers and selling news doesn't necessarily bode well for informed civilian participation, don't get me wrong. Watered-down science, politics, and economics news can obscure or belie urgency and misrepresent the grinding difficulty of policy-making.3 Of course talk-radio and TV networks do far more to manipulate and polarize citizens, and dumb down difficulty, but newspapers contribute to the problem.

The use of experts hit a nadir when the New York Times ran stories detailing WMD evidence used by the US to justify declaring war on Iraq. George W. Bush convinced Congress and a good part of the US population that Iraq had WMDs. The president is an "expert" we trust. The Times and their reporter Judith Miller helped justify the urgency of invasion by quoting other "unanimous government experts and Iraqi sources. High level government authorities in turn quoted the New York Times to wider audiences watching weekend talk shows. Miller's sources turned out to be unreliable, vaporware, if you want to continue with software analogies.

The WMD deception worked because we're practically hard-wired to depend on "experts" who feed us the bottom line on what to watch, wear, think, espouse, etc. The White House manipulated us via the Times, a trusted Times reporter, and some experts. Kinsley is right. The "experts" were merely middleman. But their presence in the story was critical to its persuasive power.

On the other hand, the presence of experts gives us valuable insight, even though readers often ignore it. Like footnotes in research and links in blogs, we can look up experts backgrounds to help us judge the quality of the story. Unfortunately, too few people do.

Rising out of "Comas and Coal Mines"

When Kinsley criticizes newspaper stories "written to accommodate readers who have just emerged from a coma or a coal mine", he ignores scads of fooled readers in our midst.

Maybe readers aren't emerging from in a coma, maybe they're stuck in a media trance. TV feeds people constant advertising about how their clothes will sparkle by switching detergents and how the loves of their lives will materialize if they drive the right car or sip the right cocoa. When fairies flit out of TV's morning cereals, a little bit of the brain pays attention (or atrophies, I'm not sure which), and over time we all start to believe the magic.

We buy lots of stuff because someone tells us it will solve out problems -- we buy and we bolster economies. But also 50% of Americans buy that global warming is a hoax. 50% believe that God created the earth a few thousand years ago. In staid, sensible Massachusetts half of voters believe that a Cosmo centerfold with a head of hair worthy of a Rograine ad will deliver them from their problems. And over 50% of Americans voted for an articulate capable president from Illinois, but now want to fire him because he didn't magical action figure they imagined. "Experts" in church, on TV, and in newspapers, spawn and encourage these beliefs.

The constant onslaught of fairy dust diminishes our attention span (Twitter-mind) and analytical abilities. Newspapers are the least worrisome of culprits. We don't vote for charismatic puffballs who drive pick-ups because of newspapers. But newspaper editors to swath the facts of stories with hoopla and hand waving to snap us out of our media trance, and momentarily hold our attention when, it's true, many people would rather be watching a cat video on YouTube. Too many facts too fast, maybe even the who, what, where, when how, would wreck our mood, so newspapers need to be cautious, need to slip the truth in judiciously.

Readers will turn online for many reasons. But it's not because the news is more concise, as Kinsley suggests, rather, because in addition to being convenient, immediate, and interactive, there's unlimited escapist distraction, and far less news, per glance, than in the Washington Post or New York Times.

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(1) As of this week, Kinsley is not longer associated with the online business site to be launched by The Atlantic Monthly

(2) Not necessarily true. Some blog posts are very long, longer than ours. And why should they be short? It costs very little to extend a 2,000 word article into a 10,000 word article.

(3) A few years ago we wrote about the New York Times' weak coverage of former President Thabo Mbeki's policies on AIDS in South Africa. Despite unrelenting illness and death Mbeki denied science, and rejected medicines, while the Times served Americans softball platitudes about Mbeki's thought processes that reflected, rather than criticized, US foreign policy. We've also written extensively about mambypamby coverage of global warming" -- there are many other issues.

Maher's Mainstream Media Anti-Vaccination Campaign

Maher Still Loco on Vaccinations:

As he has for years, Bill Maher continues to spread disinformation about vaccines. Over countless news cycles Maher has infuriated doctors, public health officials, and responsible citizens with bizarre warnings about letting governments "stick a disease into your arm".

Challenged to get a word in edgewise between his fusillades about "mercury" and "diet" and natural "immunity", doctors and scientists nevertheless patiently correct his errors. They explain that a vaccine is not "a disease" but a disabled virus that looks to the immune system like a live virus or bacteria and therefore prevents infection by the actual deadly virus or bacteria1 like polio, measles, diphtheria, or influenza.

But the talk show host persists, as is his habit. Last month, Bill "I'm also not f-king my interns" Maher baffled panelists Alec Baldwin, Chris Matthews and Maryland Governor Martin O'Malley by rehashing his concerns with vaccines. Yesterday, Maher continued with a rambling column at The Huffington Post titled "A Conversation Worth Having", saying he aimed to

"clear up a few things about my beliefs concerning the flu shot, vaccines, and health in general...I will admit, I have gone off half cocked on this issue sometimes, and often only had time on my show to explain a fraction of what needed to be explained, and for that I am sorry...I agree with my critics who say there are far more qualified people than me"

Mea culpa? Unfortunately, and spoiler alert for the 2800 word article: no. I didn't say "anyone who gets a flu shot is an idiot", Maher said, "it was twittered...my bad". Then, "vaccination is a nuanced subject, and I've never said all vaccines in all situations are bad..." Nuanced? "All vaccines"? Cagey creepy crapola -- bring it on, Maher.

Discerning Maher's Health Prescription -- When "Sometimes It's OK to Fuck with Nature"

Maher writes "I'm not a germ theory denier" and he claims "I do understand the theory of inoculation", exuding all the candor of a intelligent design proselytizer putting quotes around "the theory" of evolution. To the helpful doctor who corrects him, Maher retorts snidely "Thanks, Doc, I thought there might be a little man inside the needle. Yes, I read Microbe Hunters when I was eight." (Doesn't think the conversation is worth having?) Wikipedia-Polio_physical_therapy2.png

Cocksure and funny, Maher acts as though he's arguing about some scrutable line that any eight year old can see - you don't need to be a doctor or scientist. To the left of the line there are the OK vaccines, except, he hedges, vaccines are unproven. To the right, there are the not-OK vaccines that we should be debating, like flu vaccine. But actually, if you can't already tell, there is no line or margin, because Maher is arguing the same old run-of-the-mill anti-vaccine/medicine/science schtick you've (yawwwwnn) already heard. He allows that "sometimes it's OK to fuck with nature" and prescribe medicine, but listen to enough Maher and you realize he maligns all medicine, all vaccines.

Casting Aside Science

Sure, at first you may be confused because he mixes recognizable words into gobbledygook. Do doctors ever ask patients what they eat, he asks rhetorically? No, he answers, "and a lot can be cured with diet and a healthier lifestyle" -- then Maher adds in parentheses -- "And a lot can't [be cured]. I also understand the role of genetics and generations of artificial selection".

Despite his unassailable understanding, lets review. The risk of some diseases, like diabetes Type II, can be reduced with healthier lifestyle. Some conditions, like obesity can be prevented with diet, and losing weight concurrently reduces the risks of morbidity and mortality associated with conditions like heart disease. This isn't just semantics. Diet won't prevent crippling polio, or a flu pandemic or death of a pregnant woman, or stop a kid from succumbing to weeks of illness and a 105 degree influenza fever. And typical of Maher's machinations on science, medicine and disease, he jumps down the rabbit hole with "genetics and "generations of artificial selection". Scientists use artificial selection to breed products like corn by selecting for certain traits. Humans are not hothouse flowers, subjected to "generations of artificial selection".

How Does Maher Distinguish Himself From Dr. Beetroot?

In cajoling his audience to exercise skepticism and caution and arguing for "debate", a word that should tip anyone off to incoming falsehoods; Maher says:

"Someone needs to be representing the point of view that says the preferred way to handle flus is to have a strong immune system to begin with..."

Actually, we can think we recognize this "point of view". Take, for instance South Africa's former health minister, Dr. Manto Tshabalala-Msimang, (known derisively as Dr. Beetroot), who spent years telling South Africans to boost their immune systems against the AIDS virus with diet, beetroot and lemon.

In a familiar refrain, the South African Mbeki government insisted that Western drugs were too profit oriented and dangerous. As a result of this decision, hundreds of thousands of South Africans died from AIDS, and the dying isn't over, since infectious disease pandemics gather momentum over time. Newly elected President Zuma recently warned that the death rate from AIDS may overtake the birthrate in that country.

How is Maher's argument different than that of Tshabalala-Msimang's? Where does he draw his invisible line de-marking greedy Western medicine from essential life-saving medicine? How does this board member of the "Reason Project" (Wikipedia) dedicated to scientific and secular knowledge, identify good medicine?

How is Maher's Position Different Than A Mennonite's?

Instead of agreeing with scientists and doctors, Maher chooses to listen to Barbara Loe Fisher who he finds "extremely credible", because

"after devoting her life to studying this, she says that flu vaccines aren't proven and...points out that what we need, but do not yet have, are studies of vaccinated vs unvaccinated children."

Fisher is not a scientist or a doctor, and that's ok, anyone can educate themselves about vaccinations, eight or older. Based on her experience parenting and in public relations Fisher can certainly start a vaccination information center, appear on talk shows, testify at events like the "Vaccine Policy Analysis Collaborative: A U.S. Government Experiment in Public Engagement", and give lectures to naturopaths, chiropractors, and groups like "Body by God". Who's to say she can't?

But given that Maher says she's devoted her life to studying vaccinations, you'd think she'd understand that vaccinating some children against polio, but not others, would be medically unethical. You'd think that Maher would also see the moral quagmire.

Furthermore, unfortunately, there's lots of evidence to prove that what Fisher and Maher say is the untested theory of vaccination is flat out false. As the NYT reported in 2003:

"The last two American polio outbreaks were in Amish and Mennonite communities in 1979 and in a Christian Science school in Connecticut in 1972. Measles killed 3 students of 125 infected in a Christian Science school in 1985, and a similar-size outbreak among the Amish in 1987 and 1988 killed 2 people. In 1991, 890 cases of rubella, leading to more than a dozen deformed children, hit Amish areas."

Since then, Africans who believed rumors that vaccinations are an attempt by Westerners to spread the HIV virus or sterilize Nigerians, started a polio epidemic. The Amish also suffered polio outbreaks. Mennonites, who don't believe in vaccination but do believe in travel caused outbreaks of measles in Minnesota, then South America. Like the Amish, Mennonites don't believe in vaccinations or insurance, but do believe that hospitals should cure them for a discount, once they get sick.

How is Maher's position different then that of a Mennonite? Can we have this conversation? How does Maher square his position on vaccines with his libertarian views when people end up demanding hospital bailouts because they didn't take it upon themselves to prevent illness?

The Dredged Up "Under-reported Point of View" is Often Wrong, Concludes A Bright Person

The consequences of not vaccinating become graver and more frequent as more people refuse vaccinations. The value of vaccinations is not "debatable". Vaccinations have saved millions of lives, saved millions of dollars by keeping people out of hospitals, and boosted productivity of nations. But Maher ignores all this and calls for some cost benefit analysis, more familiar anti-science denialism.

Maher appeals to all of those who eschew facts and take solace in unpopular views.

"I'm just trying to represent an under-reported medical point of view in this country, I'm not telling a specific pregnant lady what to do...[I]t's just that mainstream media rarely interviews doctors and scientists who present an alternative point of view..."

Pregnant women and kids are most susceptible to dying from H1N1 virus. Pregnant women have decreased lung capacity that increases the threat of pneumonia, and they have decreased immunity due to their pregnancy. The reason the media doesn't interview doctors and scientists with "alternative points of view" on the subject, is because doctors and scientists agree that vaccines save lives, and that pregnant woman and parents of children shouldn't die because they've been convinced by talk show hosts to doubt the CDC, the doctors, and the scientists.

Maher's is not selling an "under-reported medical point of view", rather he's latched onto a non-medical, non-science point of view. Hmmm....why does he persist?

Bill Maher's Mainstream Media Profit Motives

Unbelievably, after flogging his point of view for years, Maher says he has no motive and expects no outcome: "[M]y audience is bright, they wouldn't refuse a flu shot because they heard me talk about it...." But his audience claps when he talks non-scientific hokum -- perhaps only because they're prompted? Either they're not thinking at all, or they're confused about science, or they're easily swayed by paranoid views, or they think they're at a gladiator show - in which case they will eventually be disappointed by the "debate." Can such folks be considered "bright" in the 21st century?

To the point, though, if Maher's especially non-bright, non-medical, non-scientific point of view weren't selling, weren't rewarded with clapping and viewers and advertising dollars, would he still be ranting on? Maher's anti-vaccination position has populist appeal that draws viewers and boosts ratings. His refutation of "mainstream media's profit motives" sells well. But lets be clear. HBO's Real Time, with millions of viewers each night, is mainstream media. What's not? Acronym Required, for instance, is not "mainstream media".

And why pick on science? Scientists are a remarkably easy target, as we noted before when John McCain chronically made fun of science research. When Maher chose to accost religion, at least 50% of Americans are quite religious, and that's a lot of potential audience members to insult. Plus, religious people can get dangerous. Other Maher campaigns have also backfired, like when Maher's remarks about military recruiting spurred one Congressman to demand that Real Time be canceled.

Considering his options then, and the groups he's already alienated, scientists make a good target. They're pretty tame, therefore easy to pick on safely, and a select target for a large potential audience, since everyone's thinking of getting the flu vaccine. Maher can perhaps equivocate about good vs. bad vaccines and fool a lot of people. So Bill Maher and his mainstream media show try to expand his audience by maligning science to become more mainstream? So they forsake scientists, but also pregnant moms and kids in the process? Is this the conversation? More or less? Bravo, talk show host!

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Photo from Wikipedia under a Creative Commons license.

1 11/19 Added "bacteria"

Acronym Required wrote on vaccinations previously, for instance in Vaccinations, Why the Worry? we wrote about the long history of rebellion against vaccinations. We also wrote about vaccinations here and in various posts and vaccines for specific illnesses.

Bill Maher's shenanigans have been will covered by scientists like Respectful Insolence here and here, by Pharyngula; by Aetiology here and here here and by many others.

Superfreakonomics authors Levitt and Dubner make it out like solving global warming is no more complicated than cooling off on the patio on a hot summer day. First, someone else puts up the umbrella, then they unwind the hose and spray all the kids so they stay cool. This may sound good to you, but it's not logical, despite what the Superfreaks insist. They're appealing to your laziness, your ennui, your fear, and your cynicism, all in the name of books and businesses that you don't hold stock in. Do you but it?

Daily Show Economics

When Steven Levitt appeared on the Daily Show to talk about their new book and the giant umbrellas that could be used to ward off climate change, Jon Stewart apologized for the collective response by scientists to Levitt and Dubner's unscientific treatment of climate change. Not only unscientific, dismissive too: Levitt told the Guardian "We could end this debate and be done with it, and move on to problems that are harder to solve", (hat tip Curious Capitalist).

Stewart commiserated to the criticized Levitt: "I'm sorry you're taking so much shit for it". But Stewart let his Daily Show audience down. For one, "Superfreakonomics" disappointed Freakonomics fans, especially those devoted libertarians and contrarians, who, though often delusional, generally manage at least a modicum of realism about climate change. Daily Show fans were also surprised that Stewart was so sympathetic to Levitt.

But if people were dismayed with The Daily Show's dismissal of climate change, they haven't been paying attention. Stewart isn't always smarter 'than that', if smarter doesn't fit the particular formula-funny he runs. Note how Stewart barely batted an eye when Levitt offered his other offensive assertion, that prostitutes should retain pimps in order to earn more money. It's true, shrugged Levitt, as if nothing can to be done because the invisible hand has sealed womens' fates the world over -- as if he didn't just twist up that statistical interpretation to get people tittering and buying books.

"The heroes turn out to be the pimps", he said. Shrug. "Get rid of the moral part" he insisted, and you have pure unadulterated economics, that's what we're about. Jon jested. Hahaha, heeheehee. Levitt shrugged again. Then the two entertainers moved on to climate change and the irrationality of environmentalists.

When Your Advertisers Are Auto Companies?

And trashing "environmentalists" isn't new territory, either, for Levitt or for Stewart. The Freakonomics blog has argued repeatedly that recycling makes little sense. The Daily Show host has previously criticized actions to lower carbon emissions, for instance "Auto-Neurotic Gas Fixation", May 20, 2009. At the time, Obama had just announced his intention to set new, ambitious CAFE standards for gas mileage. Stewart chastised him for it: "Dude...Obama...don't blow your load on mileage baby, save it for when the Chinese invade."

Stewart said that gas efficient cars, being smaller, put people "in harm's way because they're in a lighter vehicle", that "safety" was a "valid", "reasonable concern". A nod to all the automobile companies that advertise with Comedy Central perhaps? Or ignorance? You decide. We thought that this ancient Competitive Enterprise Institute (CEI) argument died back in 2007, once people thought through their elementary math and physics and realized that yes, if you run your Prius into a Hummer, you may get hurt, but the more Priuses on the road, and the fewer Hummers, the less likely you will be to run into a Hummer, therefore less likely you'll get hurt. Alas, there we were in the spring of 2009 and Jon Stewart was giving us his schoolboy version of the old auto industry fueled CEI argument.

Coincidentally, at the time -- April/May 2009 -- car sales had recently dropped to their lowest point in thirty years. A flurry of editorials pronounced the danger of small vehicles and so Stewart fit right in with The Wall Street Journal which droned on about about the "lethal effects" of CAFE standards and light vehicles. Lesson? Comedy Central is not always all that "progressive" people - really.

Just When You Thought Superfreak was Finally Gone

So Jon Stewart's accommodation to Levitt's argument isn't a surprise, nor is Superfreakonomics' bid to attract attention by rousing populist appeal. As the sequel to Freakonomics (which admittedly never did it for me), SuperFreakonomics seems to run aground the way many movie sequels do -- Rocky V, Clerks II, Caddyshack II... While maintaining sufficient audiences to grind through talk-shows, stimulate blog chatter, and generate pay-out, the authors deeply disappoint fans.

Here's a collection of about 90 blog links that criticize Chapter 5 of the book. They call the authors on many points, for instance:

  • Of distorting the science and misquoting scientists - From an atmospheric scientist (Ken Caldeira) in response to the book's quote - "Carbon dioxide is not the right villain": "I don't believe I said anything remotely like that...we should be outlawing the production of devices that emit carbon dioxide...I do see CO2 as the problem...it's like if you got shot by a bullet and you said, well, it wasn't really the bullet that was the problem, it was just that I happened to have this hole through my body..."

  • Of distorting science consensus - From many economists: "it is terribly misleading that the two scientists you quote are BOTH skeptics. What are the odds of that? Probably a billion to one, so my unavoidable conclusion is that you are deliberately trying to cast doubt on the scientific consensus."

  • Of presenting facile, improbable solutions to climate change like pumping SO2 into the atmosphere with a giant hose - From scientists: "'..thinking of geoengineering as a substitute for emissions reduction is analogous to saying, 'Now that I've got the seatbelts on, I can just take my hands off the wheel and turn around and talk to people in the back seat.' It's crazy.'"

  • Of deceiving the American public - From a congressman: "We have seen a similar effort to hoodwink, defraud, and deceive the American public now to cover up the toxicity to the world environment...I want to note a book...that basically said or asserted we don't have to control CO2..They purported to quote a scientist named Ken Caldeira from Stanford...Which is an absolute deception."

Like the Daily Show, the Superfreakonomics authors have a history of distorting reality.

Stripping Away Moralism and Giving You Freedom: The Ruse

As I wrote above, what Levitt claims, is that he simply "strips away the moralism" - then, all you have is the economics and prostitution, or economics and climate change. Glib. This is not uncommon rhetoric in economics, politics and public policy -- the ultra-rational, just do the math approach. It's used, for instance, to justify radical cost-benefit-analysis, where people argue that you can put a monetary value on everything - the price of one member of an endangered species, the price of the life of an old person, the price of the life of an infant, the price of a chemical to an industry - and otherwise complicated policy decisions fraught with difficult ethical choices can be reduced to simple math. Voilà.

The problem is, when the authors decided to write that prostitutes are better off with pimps then dug up some statistics to support that assertion, they made a moral decision. First Levitt and Dubner had to decide that this particular slant on prostitution was what they wanted to focus on, then they had to cherry pick some "data" to support it. Similarly, as we wrote in an earlier post, deciding that a male mule deer is worth $525.50, whereas a female mule deer is worth $163, while a just plain deer is worth $1, is not a decision without "moralism".

Moral sentiments are part and parcel of human decisions. Numbers and words that appear in print on a piece of paper or screen in front of you came from a formula or process derived by a human, based on that human's views, perceptions, expectations and desired outcomes. It didn't come from some superior amoralistic all-knowing power, intent on providing answers and comfort to confused humans beings -- despite what people may try to convince you.

Ironically, by asking his audience to "strip away the moralism", Levitt is appealing to ethos or pathos, but certainly not logos. He's saying -- be logical like me, I'm being logical. Shrug. But he's dismissing tons and tons of scientific proof of climate change and the need to decrease emissions as pathetic "moral" arguments (ethos), when those scientific studies are actually the logical ones (logos). He's appealing to his audience's laissez-faire tendencies, their desire to do nothing, their habits not to change, their pathos.

The Ploy: Technology will Suffice in Lieu of Action

Then, offering the equivalent of the old, chintzy plastic prize at the bottom of the box of Crackerjacks, he gives the audience something to grasp on to in the impending and threatening flood of unpleasant scientific reality, although again, it's not logical. Levitt insists that there's a simple scientific solution to solve the problem. Of course, there is no technological solution. The authors offer untested pie-in-the-sky idea that many, many scientists find problematic.

But this is what we all want to hear, right? The irrational, busy, lazy or pathetic side of all of all of us wants to be assured that electronic records will solve healthcare failures, that tsunami warning systems will prevent catastrophic losses, that ankle bracelets will prevent recidivism, that massive fences along international borders will prevent terrorism and drug trafficking, and that electronic surveillance will prevent crime. But giant garden hoses suspended up in the sky, are not even in the realm of feasible technical solutions. Yet we're so happy to slough off responsibility that Jon Stewart, although he's a modern icon of cynicism, doesn't even bother to ask questions.

Levitt plays to the audience's sentiments perfectly, first by laughing off science and scientists who present scary ideas as flimsy moralistic hogwash, then by presenting his very own special version of "science". I'm the logical one, he says, but I'm not dorky like a scientist.

His flavor of rhetoric is commonly used by those who oppose scientific evidence because it presents the type of science society likes, that which solves our problems, but is seemingly stress-free, simpler to understand than Tivo, and doesn't require you to have liked high school science. Therefore Superfreakonomics presents magic "technology solutions" in terms your average barbecuing Joe (if there is such a thing) will know and like.

According to them, solving global warming is no more complicated than cooling down on a hot summer day on the patio. First someone else puts up the umbrella to shield you. Then a kindly neighbor unwinds the hose and sprays away, and all the kids stay cool. Sound good? But its not logical. It's doesn't strip away moralism. It doesn't give you freedom. You do have to worry about global warming, you may have to change your lightbulbs. Superfreakonomics appeals not to your logical side but to your laziness, your ennui, your fear, your cynicism, all in the name of books and businesses that you don't hold stock in.

The Solution

This isn't to say that we don't need technology, quite the opposite, technology is imperative to global warming attenuation. But it's not the only effort we need, we need to conserve and to decrease emissions also.

Underlying Superfreaks' argument is the contention that people won't change. And true, people tend to squirm and stall when pressed to adjust, as we noted in "Sea Change or Littoral Disaster", Cars: Buying Cognitive Dissonance", Science Communication, Communicating Climate Change, and Climate Change, Fueling the "Debate", "Curvilinear Thinking on Climate Change", and other posts. But Real Climate's good point is that - people will change with the right incentives. People can work collectively for the better, they don't need a solution to be imposed from nigh. They do have a long history of employing morals as well as logic to solve problems, both are good, both are necessary. And given all that, it may simply be immoral for Superfreak authors to distort the truth of climate change and insist on selling implausible solutions.

Publishing: Special Thrust Privileges Some Science Papers?

Now, at PNAS Three Papers in Question:

The science journal Proceedings of the National Academy of Sciences (PNAS) offers special publication privileges to members of their Academy, a group of elite scientists chosen by other esteemed scientists based on their unique contributions to science research. Now the editorial board has retracted some of those privileges in light of papers that recently appeared in the journal.

Nature News reported on a "row" caused when PNAS published research that didn't meet the journals' standards for peer review. The dispute is now heating up. The controversy began in August when one article published on-line at PNAS forwarded a theory by author Donald Williamson, all about what he called "larval transfer hypothesis".1

Williamson suggests that the process of metamorphosis, whereby larvae turn into butterflies, arose when butterfly Leptidorae larva "mistakenly fertilized their eggs with sperm from velvet worms", as Scientific American put it (funnily twisting agency). Velvet worms Onychophora look like larvae but have completely different life cycles -- they don't turn into butterflies. According to Williamson, evolutionary transfer of genetic material causes butterflies to have essentially two lives, one as a worm-like larva, and one as a butterfly.

But there are problems with the theory. First, he offers no proof, just a "testable" hypothesis. And while interspecies fertilization is not unheard of within the animal kingdom, velvet worms are too distinct from butterflies to make this feasible, say scientists. The sperm could not fertilize such a distantly related egg and produce a viable embryo, and even if it did, it wouldn't "explain the process of metamorphosis".

Less charitably, scientists said that the paper was better suited to a a tabloid than to a science journal, and called the paper "absolutely ridiculous". They also scoffed at his attempt to show the "superficial similarity between adult velvet worms and larval moths and butterflies" with "very poorly reproduced line drawings that really need to be seen to be believed".

In short, the August PNAS paper brought a torrent of harsh criticism for the octogenarian's ideas. Moreover, while some people tolerated Williamson's submission as an attempt to generate discussion, nobody thought that PNAS should have published such a speculative paper. Scientific publishing is very competitive and many scientists who produce worthy research with real results are summarily rejected from high profile journals like PNAS. So how did the research get published, they asked, incredulous? The tale gets even more interesting.

When Push Comes to Shove

Shortly after Williaimson's PNAS article saw daylight, Scientific American published an interview with evolutionary microbiologist Lynn Margulis, an editor at PNAS who shepherded Williamson's work through the peer-review and publishing process. In recounting her story of how the paper got published, Margulis mentioned that she had been trying to publish the work for twenty years. After convincing Williamson answer how the worms fertilize caterpillars -- rather than the more conceptually challenging idea that worms breed with butterflies, she told SA it took 6 or 7 peer reviews before she got 2 or 3 that were positive enough to push the paper through to publication. More eyebrows raised in the science community.

It turns out that Lynn Margulis "communicated" Williamson's paper to PNAS, a method of publishing offered to Academy members that differs from "submissions". Via this method, members can suggest for publication papers by non-members, along with reviewers selected by the member. PNAS recently announced it will eliminate this "Track I" publishing in 2010. In the meantime PNAS editors will not publish Williamson's paper in print edition pending further discussion with Margulis about the review process.

But now it's not just that paper. Another PNAS paper by Margulis and co-authors that's being questioned apparently proposes a treatment for Lyme disease that's "800" times more effective than doxycycline -- "it is very important to get this paper published", co-author Oystein Brorson told Nature.

A third paper in question is a computational biology paper by an adjunct professor of the Margulis lab. PNAS has asked Margulis to withdraw that paper because of problems with the methods. Margulis told Nature she would do no such thing, and when asked in turn for comment, PNAS told Nature: "We don't want to respond to any questions or complaints she [Margulis] has through the media." Sounds like more entertainment is forthcoming.

The three PNAS papers all circle themes that Margulis has been pursuing for decades -- Spirochetes, desiccation, spores, symbiosis and more symbiosis than you'd ever believe, and disease. Is the recent spate of publishing from the Margulis camp a final push for these ideas? And even more controversial ones?

Another 2009 paper has been published on-line in the (less well-known) journal Symbiosis (another journal that Margulis edits), by the same authors -- Hall, Brorson, Margulis and others. This "position paper" proposes that antibiotic treatment of Lyme and Syphilis, both caused by Spirochetes, induces the formation of cysts, or "round bodies", that then revert to their original Spirochete form in a favorable (antibiotic free) environment, causing secondary infections, long-term human symbioses, and compromised immunity.2

Although the abstract is pretty straight-forward, the paper quickly leaps out on a limb to suggest that AIDS is not caused by HIV but by Spirochete round bodies. Again, there's no evidence. The authors draw tenuous connections between quotes made by public health officials after a 2007 HIV vaccine trial, and their own round body theory of AIDS. They reason that HIV seems not to infect heterosexual partners as much as men who might be infected with syphilis but not fully treated with antibiotics even though medical professionals say they are. So the authors have an idea:

"Is the situation [AIDS] better described as an obligate and ancient symbiosis where the bionts (spirochetes and humans) are integrated at the behavioral, metabolic and genetic level rather than a new viral infection such that HIV equals AIDS? ...We urge that the possible direct causal involvement of spirochetes and their round bodies to symptoms of immune deficiency be carefully and vigorously investigated."

So then HIV might not be caused by a virus but by Spirochete round bodies. See? Someone test this right away.

Forget Crabs, Look Out For Round Bodies and Symbiosis

Margulis told Nature her attitude about the three PNAS papers in question: "If they definitively reject these papers I will make it very clear to the reading public (because they make it clear in their anonymous letters) that, as usual, they don't like my ideas." Two years ago, we posted on Margulis's controversial ideas and public relations skirmishes. Our post followed her debut on PZ Myers blog, where unchallenged, she forwarded her idea that HIV didn't cause AIDS. If HIV causes AIDS than why doesn't NIH write back to me, she asked? We wrote:

"Margulis relishes controversy and slings mud far better than most people, a well-honed and essential skill....[but] famously, despite her formidable offense skills, she forever portrays herself as someone who has been pushed in a mud puddle."

The PNAS controversy is interesting, although it wouldn't leap out at everyone so much if the papers in question weren't so blatantly ludicrous. PNAS's publication "favoritism" is far from unusual in the science world. And really, Margulis has been publishing these ideas for years, drawing connections based on thin research (often foreign, often Russian, somehow lost on Americans), and asking the science community to run some experiments to test her ideas. In our previous post we talked about her theory of Spirochete symbiosis forming nerves (remember "behavior" from the quote above?):

"Think of the nerve as coming from what had formerly been a bacterium, 'trying' but unable to rotate and swim. Thought involves motility and communication, the connection between remnant spirochetes. All I ask is that we compare human consciousness with spirochete ecology."

"All I ask". That was in 1991. But the gulf between what she "asks" and a warm reception from scientists has grown as science has advanced. Williamson is an 87 year old retired scientist, who himself is no stranger to forwarding controversial ideas. Sketched drawings weren't so ludicrous 60 years ago when he was starting. But now, the idea that a paper could simply describe what you see, like generations and generations of cell biology papers before us, seems ridiculous. As an educator at Princeton said recently, "The days of sort of naturalistic walking around and looking at flowers are long gone". (Look at the emphasis on clinical description in this excerpt from a ptomaine poisoning paper from the early 1900's. Williamson was a scientist not too long after that.)

Margulis has always published in PNAS. Some of the labs' older papers have similar themes and a little research. But it's a different world now. Margulis still has the prestige to gather a cast of characters around her in symbiotic relationships, to continue to push ideas out, and to entertain admirers like PZ Myers and his followers. But while her fame draws admirers and moths it also draws vipers, many of whom are now online.

PNAS claims they were going to change their Track I policy anyway. OK, sure, but no doubt the deluge of online criticism didn't tempt them to tarry with the announcement. Just as high tech science has redefined what a good science paper looks like, online science criticism has become blood sport. And that's a good thing, don't get me wrong. But imagine what would we'd learn if all papers and journal publication policies got such a thorough raking over?

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1 Proceedings of the National Academy of Sciences: Caterpillars evolved from onychophorans by hybridogenesis Donald I. Williamson, Communicated by Lynn Margulis, University of Massachusetts Amherst, Amherst, MA, July 24, 2009 (received for review May 19, 2009)

2SYMBIOSIS Vol. 47, No. 1 (2009) Position paper. Spirochete round bodies. Syphilis, Lyme disease & AIDS: Resurgence of "the great imitator"? L. Margulis, A. Maniotis, J. MacAllister, J. Scythes, O. Brorson, J. Hall, W.E. Krumbein, and M.J. Chapman

Notes September 25th

  • 2nd Hand Smoke Bans Reduce Heart Attacks: According to two analyses of combined study data on second hand cigarette smoke, town or community enforced smoking bans reduce heart attacks by 17% after one year, and after three years the number of heart attacks decreases by at least 26%. The Journal of the American College of Cardiology published one analysis. UCSF researchers analyzed the same data and also found a 17% decrease after on year, which after three years became a 36% decrease in heart attacks. The journal Circulation published the UCSF results.

    While states and communities have increasingly enacted smoking bans, the tobacco industry generally rejects regulation. As John Singleton, spokesman for Reynolds American told the Wall Street Journal: "Our current position is to let the market take care of the issue". (09/21/09 "The Case for Bans on Smoking") On this argument however, the tobacco industry's reasoning might be losing sway. Smoking bans are catching on the world over, even in hard to imagine places like the country of Turkey's bars and restaurants.

  • AIDS Trial: New Results, No Answers

    Scientists stopped the last clinical trial of an AIDS vaccine in 2007 when results showed the vaccine increased the HIV infection. They vowed to reconsider their strategy toward AIDS, especially with regards to clinical trials. Scientists postulated that the flush funding environment and political pressures pushed trials forward too quickly. Now the sometimes exasperating path of scientific research has taken a new turn in AIDS research and scientists have a new quandary.

    A recent HIV clinical trial in Thailand testing a combination of two drugs that had previously failed in clinical trials showed tenuously positive results. The US Army, National Institutes of Health, Thai Health Ministry, and Sanofi Aventis collaborated on the trial, giving vaccines to 16,400 volunteers who were not considered high risk. The new project combined AidsVax, an HIV derived protein, with Alvac HIV, a genetically engineered canarypox virus that contains HIV genes. 51 of the vaccinated individuals contracted HIV and 74 of the unvaccinated individuals became HIV positive, which translated to about a 30% prevention efficacy rate. Though this vaccine is a long way from being considered successful, scientists are buoyed by any news that's positive. The trial suggests that this vaccine could be effective if it were improved.

    The quandaries: First, scientists don't understand how two failed drugs add up to something that looks better or vaguely successful. Second, how and why does the combination vaccine prevent the symptoms of AIDS, if it does, without lowering the viral load -- the amount of HIV measured in the bloodstream of infected individuals? Perplexing. More research needed.

    Treatment is expanding but without prevention of HIV transmission, AIDS will remain a losing battle. So for now, "ABC", abstinence, "be faithful" (limit numbers of partners), and condoms, remain the best HIV infection prevention techniques. The good news for researchers maybe is that perhaps AIDS vaccine research has been kept alive.

    Acronym Required wrote previously about AIDS in Preventing HIV/AIDS: Back to the 1980's, New Directions for AIDS Research Funding", Mbeki's AIDS Legacy and Ours, Public Health, AIDS, Mbeki and the Media, Zimbabwe: Hopeful News for HIV/AIDS Prevention?, Burma and AIDS - Politics Rules", South Africa: Peddling Beetroot, Courting AIDS, and others.

    October UPDATE: Further statistical analysis of this trial showed that the results weren't statistically significant.

  • Flavored Tobacco Banned: This week the FDA enacted the law banning flavored cigarettes. The ban does not include menthol cigarettes. Altria Group, formerly Phillip Morris, favors the ban, and not coincidently, is marching ahead with acquisitions to solidify its market leader status in smoke-free tobacco products and also expanding its international tobacco holdings. We previously wrote about the cigarette regulation in The FDA and Cigarettes.

  • FISA in the Obama Administration: With part of the USA Patriot Act up for renewal, the House is debating intrusive pieces of the legislations that allow privacy intrusion by wiretap, allow the government by access to business records, and allow surveillance of "lone wolf" suspects who have no known links to terrorists.

    One of the more controversial features gave the FBI authority to deliver National Security Letters to businesses and demand information about individual customers. The Letter recipients are ordered to be completely mum about receiving the Letters, meaning they can't tell their spouses, never mind their customers. Critics charge the National Security Letters provision of the Patriot Act violates the First Amendment. According to the Washington Independent's coverage of yesterday's House Judiciary Committee Hearing, this provision has been widely used and abused by government officials.

  • Network Neutrality The FCC upheld the principle of network neutrality this week. FCC chairmain Julius Genachowski's "open internet" is now online, along information, public outreach and requests for comments on broadband and the internet. The FCC site is one of the better ones, sharing and soliciting information on broadband and networking as the agency looks to deploy technology more widely and efficiently across the US for uses like healthcare and "telework".

    Of course, in opposition to network neutrality, a coalition of conservative legislators called the American Legislative Exchange Council (ALEC), criticized the principle. Not surprisingly, the group opined that "the market" should be allowed to assure openness unfettered by government.

  • PG&E Leaves US Chamber of Commerce: The Northwest energy company PG&E has left the business association, citing the group's refusal to reconcile its rhetoric with the facts of global warming.

  • Born Free: "Nature Communications" will begin accepting submissions to their new open-access "born digital publication" in October 2009. The first issue will be published in 2010. According to the press release from Nature Publishing Group (NPG) "authors will be able to publish their work either via the traditional subscription route, or as open access through payment of an article processing charge (APC)."

    "New Scientist points to a "puzzling passage" in the press release, where NPG explains that the new journal will publish papers from all science disciplines "of the highest quality, without necessarily having the scientific reach of papers published in Nature and the Nature research journals." To understand, New Scientist followed up with Ruth Francis, NPG spokesperson, who said that Nature Communications will, as New Scientist put it, "feature research that is more focused and less generally applicable than work that typically appears in Nature" from "fields that aren't covered by the [Nature] research journals".

    The journal will be peer reviewed, NPG stresses in its press release. It will employ a "rapid, yet rigorous, peer-review process", meaning "efficient peer review with fast publication", that is "rapid and fair publication decisions based on peer review, with all the rigour expected of a Nature-branded journal". So...Nature Communications, not to be confused with "bulk publishing of low-quality papers", which, as we noted, caused such a stir last year. Nature has long explored open-access publishing. We look forward to the new journal.

Notes: Another September Issue

  • In the Beginning...Mini-T: Before Homo sapiens, before meteors annihilated Tyrannosaurus rex, before that massive dinosaur bounded over the earth, a smaller, similar looking dinosaur existed. Raptorex kriegsteini had 1/90th the body mass of the ~2.5 ton T.rex and lived about 65 million years earlier. Palais_de_la_DecouverTrex.jpg A raptorex fossil found in China had the same body features as T. rex and scientists think that the specialized predatory morphology -- large jaw, small front legs, powerful back legs -- grew larger in future generations, evolving to become T. rex. The photo is of a T. rex is from Wikipedia Commons.

  • New Science Journalism: Futurity formally launched September 15. Futurity, not to be confused with "Singularity", is a collective on-line publication effort by leading research universities. The universities will promote their science accomplishments and fill the gaps of dwindling newspaper science coverage. Articles will be submitted by members of the Association of American Universities (AAU), with Stanford, University of Rochester, and Duke leading the effort. Critics point out that aggregating news generated by University PR departments (20% fact, 80% big story?) won't provide readers the same unbiased perspective as proper journalism coverage. True, but we can't ignore the fact that a significant amount of science coverage consists of press releases anyway.

  • Swine Flu Fallout: The H1N1 pandemic not only causes havoc for humans who fall ill, college campuses trying to manage the illnesses, and health workers. The pandemic effects society and economy in ways you don't necessarily think of. Consider, for instance:

      1.) Egypt can't keep up with its street garbage. As we wrote earlier this year, Egypt set out to kill all the pigs in the country, an unwarranted action. Many belonged to Christian herders whose pigs cleaned the streets of millions of tons of organic waste per year. Now parts of Cairo are knee deep in garbage.

      2.) Pork belly futures, which fell from 89 in April 2009 to 40 in August 2009, have now rebounded to their previous high.

  • A Chance To Recalculate the Bush Ozone Ruling?: The Environmental Protection Agency (EPA) announced last week that it would reexamine the standard set by the Bush administration for ozone which had motivated states to sue the EPA. Ozone is a health hazard at certain levels, and in 2008, the agency set a new standard at 75 parts per billion (ppb), down from 84 ppm. The EPA heralded this as a life-saving improvement, but according to science advisors of the Clean Air Scientific Advisory Committee (CASAC), only 60-70 ppm will prevent deaths.

    Susan Dudley headed the Office of Information and Regulatory Affairs (OIRA) in 2008 when the Bush administration decision was made. OIRA influenced the outcome of Bush's ozone ruling by sending a series of memos to the EPA impeding the ozone ruling and killing a secondary standard which would have triggered certain safety measures in some weather conditions. We wrote last year how Susan Dudley had argued on behalf of industry prior to her tenure at OIRA, that "smog was beneficial because it protected individuals from ultraviolet radiation, and that since asthma rates were associated with poverty, a smog ruling would have the 'perverse effect' of costing communities money, which would in turn increase poverty and asthma." Her's was a twisted cost-benefit analysis.

    Now Cass Sunstein heads OIRA. According to the Environmental Defense Fund (EDF), the EPA has calculated the benefits to society from the now thriving environmental industry and determined that those monetary benefits outweigh the costs of the standard. So is cost-benefit ok when the outcome favors the politics you prefer?

  • Team Players: Researchers at Oxford University published a paper in Biology Letters reporting that more elevated endorphin levels associated with team sports like rowing than single player activities.

  • Justice Department On Proposed Google Books Settlement The Justice Department said Friday that the settlement needed changes to address copyright, class-action and antitrust issues, and urged the Federal Court to reject the settlement. However, the government added that current discussions between the parties were productive and should continue.

  • EPA and NHTSA, Together At Last, Overlapping: The EPA also proposed new carbon dioxide emissions this week, in concert with the National Highway Traffic Safety Administration (NHTSA). The new rule would lower fleet standards to 35.5 mpg by 2016. As well, cars would be allowed to emit 250 grams of CO2/mile by 2012, as opposed to the current rule of 265 grams of CO2/mile. The Association of International Automobile Manufacturers, Inc. (AIAM), and Senator Markey praised the agencies for their collective effort.

    A coordinated effort from the two agencies that oversee automobile emissions and mileage efficiency has long been a goal of industry and policy makers, though a goal sometimes cynically pursued. We also wrote about EPA/NHTSA overlap here and here. The standards will cover model years 2012 through 2016, and as the Obama administration bills it: "the automobile manufacturers would be able to build a single, light-duty national fleet that satisfies all federal requirements as well as the standards of California and other states."

  • Migraines: McCain's Bane: Cindy McCain is heading to Congress, reports the New Yorker, to lobby for money to study migraine headaches. And you thought perhaps you'd heard the last of McCain science research jokes? She told the American Headache Society (AHS):

    "For the first time in my life, I'm going to go to Congress, and I'm going to be tenacious and be forceful and be honest and tell them that it's time. If you can give five million dollars to study flatulence in cows and its effects on the ozone layer, you can give me some money for migraine research."

    Migraines are, of course, a debilitating problem -- that's no joke. As McCain details in her talks, migraine headaches are sometimes set off by "triggers" -- foods like chocolate, or particular odors or chemicals. McCain reports that her company's beer, Stella Artois, contains sulfites "out the wazoo" that trigger her headaches. Travel is full of trouble. Sometimes a perfume bottle breaks and the debilitating noxious fumes cause her to repack her bags and fly home. Foreign food smells prove treacherous too, she says: "...like...forgive me, but the scent of cooking dog"

    She didn't say which countries serve the offensive "dog", often a subject of nasty rumors, or how one can tell that it's not chicken, water buffalo, or frog. But fortunate she is then, that her role is the ambassador of headaches not the ambassador of smoothing international relations with her would-have-been President husband.

Musing Darwin's Musical Muse

Scientists' Inspirations As They Tell It

Darwin wasn't all ships, and biology, and empirical notes on science, he also appreciated the arts, especially music, at least he did before he wrote: "the musical department of my brain atrophied". J.F. Derry wrote in the science history journal Endeavor, how Darwin's wife Emma influenced the famous scientist, in "Bravo Emma! Music in the life and work of Charles Darwin" 1. Apparently Mrs. Darwin played the piano nightly, recitals that Mr. Darwin enjoyed while "lying quietly on the sofa". But her musical influence went beyond that. The article describes how the music perhaps even helped mould Darwin's take on evolution. Darwin wrote in one letter about "The Descent of Man".

"I conclude that musical notes and rhythm were first acquired by the male or female progenitors of mankind for the sake of charming the opposite sex."

And As the Wives Tell It

However some might tell the story of who influenced who in the Darwin family differently. Britain appointed Scottish poet, playwright, and creative director of Manchester Metropolitan University's writing school, Carol Ann Duffy, poet laureate last Friday. Duffy wrote in her collection, "The World's Wife", about women's roles and contributions to famous men. Duffy humorously chronicles, "the rage of women disappointed, discarded or overlooked by men", as the New York Times puts it, men such as Quasimodo and Rip Van Winkle. She characterizes the wives of real men too. Her poem "Darwin's Wife" (via NYT) goes like this:

7 April 1852
Went to the Zoo
I said to him -- Something
      about that chimpanzee over
      there
reminds me of you

Duffy holds the post that for the 341 previous years the job had been held by men such as Geoffrey Chaucer, Lord Alfred Tennyson, William Wordsworth and Ted Hughes.

1Endeavor, March, 2009: doi:10.1016/j.endeavour.2009.01.005

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